Redaporfin - CISMeF

Preferred Label : Redaporfin;

NCIt synonyms : LUZ 11;

NCIt definition : A bacteriochlorin-based photosensitizer, with antineoplastic activity upon photodynamic therapy (PDT). Following intravenous administration, redaporfin preferentially accumulates in hyperproliferative tissues, such as tumors. Local application of laser light at the tumor site results in the absorption of light by this agent and a photodynamic reaction between LUZ 11 and oxygen. This results in the production of reactive oxygen species (ROS), which includes singlet oxygen molecules, the superoxide ion, and other cytotoxic free radicals. The formation of ROS induces free radical-mediated DNA damage and cell death.;

UNII : ZP3QP1H44W;

InChIKey : CKRVBMUJCFKRND-ZXWMLXKTSA-N;

CAS number : 1224104-08-8; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 1224104-08-8 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

NCI Metathesaurus CUI : CL471817;

Details

Origin ID

C114382;

UMLS CUI

C4307668;

Automatic exact mappings (from CISMeF team)
- redaporfin [MeSH Supplementary Concept]
- redaporfin [MeSH concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- redaporfin [MeSH Supplementary Concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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