Lugol's Solution

Preferred Label : Lugol's Solution;

NCIt synonyms : Lugol's Iodine;

NCIt definition : A solution composed of iodine and potassium iodide, which can be used as a reagent and antiseptic, with potential use in cancer diagnosis. The iodine in Lugol's solution selectively binds to alpha-1,4 glucans found in polysaccharides, such as glycogen. Lugol's solution reacts with glycogen in normal, healthy non-keratinized, squamous epithelium and the iodine-glucan complex stains the glycogen-containing cells dark brown. Cancer cells are devoid of glycogen, so these cells will stay unstained. The presence of cancer cells can be detected by the degree of staining and the neoplastic cells can be surgically removed. High-grade intraepitheial neoplasia has almost no glycogen-containing epithelium.;

Details

Origin ID

C114292;

UMLS CUI

C0065234;

Automatic exact mappings (from CISMeF team)
- Lugol's solution [MeSH concept]
- Lugol's solution [MeSH Supplementary Concept]
Semantic type(s)
- Indicator, Reagent, or Diagnostic Aid [UMLS semantic type]
- Inorganic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Lugol's solution [MeSH Supplementary Concept]
- Lugol's solution [MeSH concept]
- potassium triiodide [Substance BNPC]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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