Preferred Label : Survivin/p53/HER2 Antigen-loaded Autologous Dendritic Cell Vaccine;
NCIt synonyms : Survivin/p53/HER2 Antigen-loaded Autologous DC Vaccine;
NCIt definition : An autologous dendritic cell (DC) vaccine loaded with tumor-associated antigens (TAAs)
derived from survivin, p53 and human epidermal growth factor receptor 2 (HER2 or ERBB2),
with immunostimulating and antineoplastic activities. Upon administration, this DC
vaccine may elicit a potent cytotoxic T-cell (CTL) response against tumor cells expressing
these TAAs, resulting in tumor cell death. Survivin, p53 and HER2 are essential in
neoplastic growth, and are considered to be universal tumor antigens.;
NCI Metathesaurus CUI : CL471793;
Origin ID : C114285;
UMLS CUI : C3827891;
Semantic type(s)
- concept_is_in_subset
