Preferred Label : 16-Hydroxyestrogen;
NCIt synonyms : 16-Hydroxyestrogens; 16-Hydroxyestrogen Compound;
NCIt definition : Any metabolite formed during the catabolism of estrogens by the liver through the
hydroxylation of the carbon at position 16 by the enzymes, cytochrome P450 3A4 and
1B1. The 16-hydroxyestrogens may have high estrogenic activity and preferential formation
of 16-hydroxyestrogen metabolites may be associated with an elevated risk for breast
cancer.;
Origin ID : C113817;
UMLS CUI : C3827305;
Semantic type(s)
- concept_is_in_subset
