Preferred Label : 2-Hydroxyestrogen;
NCIt synonyms : 2-Hydroxyestrogens; 2-Hydroxyestrogen Compound;
NCIt definition : Any metabolite formed during the catabolism of estrogens by the liver through the
hydroxylation of the carbon at position 2 by various cytochrome P450 (CYP) enzymes,
including CYP3A4, 1A1 and 1A2. The 2-hydroxyestrogens have minimal estrogenic activity
compared to the parent compounds.;
Origin ID : C113816;
UMLS CUI : C3831771;
Semantic type(s)
- concept_is_in_subset
