T Helper 17 Cell

Preferred Label : T Helper 17 Cell;

NCIt synonyms : Th17 Cell; Th17;

NCIt related terms : Th17 cells;

NCIt definition : A subset of helper T-lymphocytes which synthesize and secrete the interleukins (IL), IL-17A, -21 and -22. These cytokines mediate inflammation by increasing chemokine production, which leads to the recruitment of both monocytes and neutrophils to sites of infection or inflammation. Th17 cells modulate both host immunity against extracellular bacteria and fungi and inflammation. Overexpression of these cells is associated with tissue injury caused by autoimmune diseases.;

Details

Origin ID

C113815;

UMLS CUI

C2936411;

Anatomic structure is physical part of
- Hematopoietic and Lymphoid Tissue [NCIt concept]
- Lymphoid Tissue [NCIt concept]
Automatic exact mappings (from CISMeF team)
- Th17 cells [MeSH Descriptor]
- Th17 cells [MeSH concept]
Semantic type(s)
- Cell [UMLS semantic type]
UMLS correspondences (same concept)
- Th17 cells [MeSH Descriptor]
- Th17 cells [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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