Preferred Label : Oxidized Avidin;
NCIt definition : An oxidized form of the glycoprotein avidin, that can be used as a linking agent for
tissue-pretargeted radionuclide therapy. Upon intralesional administration, the aldehyde
groups of oxidized avidin strongly bind to the amino groups on tissue proteins, via
the formation of Schiff bases. As avidin is able to strongly bind to biotin, intravenous
administration of radiolabeled biotin may lead to the selective eradication of the
pre-targeted tumor cells.;
Drug name : AvidinOX;
NCI Metathesaurus CUI : CL471781;
Origin ID : C113800;
UMLS CUI : C3828678;
Semantic type(s)
- concept_is_in_subset
