Preferred Label : Inosine Dialdehyde;
NCIt synonyms : 9H-purine-9-acetaldehyde, alpha-(1-formyl-2-hydroxyethoxy)-1,6-dihydro-6-oxo-, (R-(R*,
R*))- (9CI); diglycolaldehyde, alpha-(hydroxymethyl)-alpha'-(6-hydroxy-9H-purin-9-yl); Diglycoaldehyde; 9H-purine-9-acetaldehyde, alpha-(1-formyl-2-hydroxyethoxy)-1,6-dihydro-6-oxo-, (R,R)-
(8CI); IdA;
NCIt related terms : Inox; 9H-Purine-9-acetaldehyde, .alpha.-(1-formyl-2-hydroxyethoxy)-1,6-dihydro-6-oxo-, (R,R)-
(8CI); Diglycolaldehyde, .alpha.-(hydroxymethyl)-.alpha.'-(6-hydroxy-9H-purin-9-yl)-; 9H-Purine-9-acetaldehyde, .alpha.-(1-formyl-2-hydroxyethoxy)-1,6-dihydro-6-oxo-, (R-(R*,
R*))- (9CI);
NCIt definition : A toxic purine analogue. Inosine dialdehyde inhibits ribonucleotide reductase, resulting
in decreased synthesis of DNA, RNA, and proteins, and G2/M-phase cell cycle arrest.
This agent also forms stable covalent crosslinks in proteins, thereby inhibiting the
activity of enzymes involved in nucleic acid synthesis. (NCI04);
UNII : 4613T5ZY7G;
CAS number : 23590-99-0;
Molecule name : Wy-5321;
NSC code : 118994;
Codes from synonyms : NSC0118994;
Origin ID : C1136;
UMLS CUI : C0063555;
Currated CISMeF NLP mapping
- Semantic type(s)
- UMLS correspondences (same concept)
- concept_is_in_subset
