CHN2 wt Allele

Preferred Label : CHN2 wt Allele;

NCIt synonyms : Chimerin 2 wt Allele; CHN2-3; ARHGAP3; RHOGAP3; BCH;

NCIt definition : Human CHN2 wild-type allele is located in the vicinity of 7p15.3 and is approximately 392 kb in length. This allele, which encodes beta-chimaerin protein, plays a role in both the proliferation and migration of smooth muscle cells. Decreased expression of this gene is associated with high-grade gliomas and breast tumors, and increased expression of this gene is associated with lymphomas. Mutations in this gene have been associated with schizophrenia in men.;

GenBank Accession Number : NM_004067;

Details

Origin ID

C113548;

UMLS CUI

C3715041;

Automatic exact mappings (from CISMeF team)
- Chimerin 2 [OMIM gene]
- Chorea, benign hereditary [OMIM Phenotype]
- NK2 homeobox 1 [ORDO Gene]
OMIM relation
- Chimerin 2 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_plays_role_in_process
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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