NCIt synonyms : IGJ; JCH; Immunoglobulin J Polypeptide, Linker Protein for Immunoglobulin Alpha and Mu Polypeptides
Gene; IGCJ; Joining Chain of Multimeric IgA and IgM wt Allele;
NCIt definition : Human JCHAIN wild-type allele is located the vicinity of 4q13.3 and is approximately
23 kb in length. This allele, which encodes immunoglobulin J chain protein, is involved
in the joining of antibody monomer chains. Mutations in this gene are associated with
both renal artery obstruction and fibromuscular dysplasia.;