NCIt related terms : Indole-3-methanol; 3-Hydroxymethylindole;
NCIt definition : A naturally occurring, orally available cleavage product of the glucosinolate glucobrassicanin,
a natural compound present in a wide variety of plant food substances including members
of the family Cruciferae with antioxidant and potential chemopreventive properties.
Indole-3-carbinol scavenges free radicals and induces various hepatic cytochrome P450
monooxygenases. Specifically, this agent induces the hepatic monooxygenase cytochrome
P4501A1 (CYP1A1), resulting in increased 2-hydroxylation of estrogens and increased
production of the chemoprotective estrogen 2-hydroxyestrone.;
Alternative definition : NCI-GLOSS: A substance that is being studied as a cancer prevention drug. It is found
in cruciferous vegetables.; CRCH: An indole with a carbinol group (-C2OH) attached at the 3 position of the pyrrole
ring. The chemical structure is C1 CC C2C( C1)C( CN2)CO.;
UNII : C11E72455F;
CAS number : 700-06-1; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 700-06-1
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Currated CISMeF NLP mapping