NCIt definition : A membrane vesicle/ribosome preparation derived from the bacterium Serratia marcescens
with immunomodulatory activity. ImuVert triggers interferon (IFN) gamma production
through binding the low affinity IgG Fc receptor type III (CD16) on natural killer
(NK) cells. This agent works synergistically with interleukin-2 further enhancing
IFN gamma production. In addition, ImuVert is capable of inducing peripheral blood
mononuclear cells (PBMC), from the cord blood of newborn infants lacking NK activity,
to exhibit NK activity.;