Preferred Label : Allogeneic Glioblastoma Stem-like Cell Line Lysate-pulsed Autologous Dendritic Cell
Vaccine;
NCIt definition : A cell-based cancer vaccine composed of autologous dendritic cells (DCs) pulsed with
lysates from an allogeneic glioblastoma (GBM) stem-like cell line, with potential
immunostimulatory and antineoplastic activities. Upon administration allogeneic glioblastoma
stem-like cell line lysate-pulsed autologous dendritic cell vaccine exposes the immune
system to GBM stem cell antigens, which may result in cytotoxic T lymphocyte (CTL)
and antibody responses against GBM cells. This leads to GBM cell lysis. GBM stem-like
cells contain a specific range of antigens that are essential for the neoplastic growth
and survival of GBM cells.;
NCI Metathesaurus CUI : CL458143;
Origin ID : C113296;
UMLS CUI : C3831562;
Semantic type(s)
- Cell [UMLS semantic type]
- concept_is_in_subset
