Receptor-Activated SMAD

Preferred Label : Receptor-Activated SMAD;

NCIt synonyms : rSMAD; Receptor-Regulated SMAD; Receptor-Activated SMADs; R-SMAD; R-SMADs; Receptor-Regulated SMADs; rSMADs;

NCIt definition : A family of transcription factors that are activated by signaling mediated by tumor growth factor-beta (TGF-beta) superfamily ligand-receptor interactions. Once activated, R-SMADs play a role in the positive regulation of TGF-beta responsive gene expression.;

NCIt note : The R-SMAD family includes SMAD1, SMAD2, SMAD3, SMAD5, and SMAD8.;

Details

Origin ID

C113248;

UMLS CUI

C3828360;

Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_product_has_biochemical_function
- Transcription Coactivator [NCIt concept]
gene_product_plays_role_in_biological_process
- Receptor Signaling [NCIt concept]
- Transcriptional Activation [NCIt concept]

Keyword's position in hierarchy(ies) :

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