Creatine Kinase

Preferred Label : Creatine Kinase;

NCIt synonyms : Phosphocreatine Kinase; Creatine Phosphokinase; Creatine Phosphotransferase; ATP:Creatine N-Phosphotransferase; ATP:Creatine Phosphotransferase; CPK; Adenosine Triphosphate-Creatine Transphosphorylase; CK;

NCIt definition : An enzyme complex that can reversibly convert ATP and creatine to phosphocreatine and ADP. Cytosolic creatine kinases are comprised of homodimers or heterodimers of creatine kinase B-type protein and creatine kinase M-type protein. Mitochondrial creatine kinases are octomers comprised of either four homodimers of creatine kinase U-type, mitochondrial protein or four creatine kinase S-type, mitochondrial protein homodimers.;

Details

Origin ID

C113245;

UMLS CUI

C0010287;

Automatic exact mappings (from CISMeF team)
- CPK [MedDRA LLT]
- Creatine kinase.MM [LOINC component]
- Phosphatidylinositol 3-kinase, class 2, alpha [OMIM gene]
- cpk [BNCI exam]
- creatine kinase activity [GO term]
- creatine kinase, MM form [MeSH Descriptor]
Currated CISMeF NLP mapping
- Creatine kinase [MedDRA LLT]
- Creatine kinase [LOINC component]
- Creatine kinase (substance) [SNOMED CT concept]
- Creatine phosphokinase [MedDRA LLT]
- creatine kinase [MeSH concept]
- creatine kinase [SNOMED Notion]
- creatine kinase [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Creatine kinase [LOINC component]
- Creatine kinase (substance) [SNOMED CT concept]
- creatine kinase [SNOMED Notion]
- creatine kinase [MeSH Descriptor]
- creatine kinase [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_product_plays_role_in_biological_process
- ATP Hydrolysis [NCIt concept]
- Phosphorylation Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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