Preferred Label : Zinpentraxin Alfa;
NCIt synonyms : Recombinant Human PTX2; Recombinant Human Serum Amyloid P; Recombinant Human Pentraxin 2; Pentraxin 2;
NCIt definition : A fully recombinant form of the human pentraxin 2 (PTX2) protein with potential antifibrotic
activity. Upon intravenous administration, zinpentraxin alfa may inhibit myofibroblast
generation by preventing the differentiation of circulating monocytes into fibrocytes
and profibrotic macrophages. PTX2 is a circulating plasma protein that belongs to
the class of pattern recognition receptors (PRR) of the innate immune system.;
UNII : F68WAH6N5E;
CAS number : 1387453-03-3;
Molecule name : PRM-151; PRM 151;
Codes from synonyms : 398;
Origin ID : C113177;
UMLS CUI : C5667141;
Semantic type(s)
- UMLS correspondences (same concept)
- PRM-151 [MeSH Supplementary Concept]
- concept_is_in_subset
