Preferred Label : Low Shear Granulation;
NCIt related terms : Granulation, Low Shear; Low-Shear Tumble Granulation;
NCIt definition : The use of a series of integrated steps whereby a dry powder is conditioned by wetting
or is melted to form a plasticized mass that with the aid of low shear forces, yields
particles possessing characteristic dimensions and density.;
Alternative definition : FDA: A series of integrated steps whereby a dry powder is conditioned by wetting or
is melted to form a plasticized mass that with the aid of low shear forces (e.g.,
tumbling, agitation), yields particles (e.g., spheres and pellets) possessing characteristic
dimensions and density; excludes operations used to obtain an intimate uniform mixture
of the ingredients prior to being fed to the granulation equipment (e.g., convection
or diffusion mixing).; PQCMC: Powder densification and/or agglomeration by the incorporation of a granulation
fluid into the powder with low-power-per-unit mass, through rotation of the container
vessel and/or intensifier bar.;
Origin ID : C113012;
UMLS CUI : C3829249;
Semantic type(s)
- concept_is_in_subset
