Preferred Label : Fluidized Hot Melt Granulation;
NCIt related terms : Granulation, Fluidized Hot Melt; Hot-melt Granulation;
NCIt definition : The process of forming granules using meltable binders to agglomerate dry powders
under elevated temperatures resulting in granules suitable for filling or compression.;
Alternative definition : FDA: Granulation using meltable binders to agglomerate dry powders under elevated
temperatures resulting in granules suitable for filling or compression.; PQCMC: An agglomeration process that utilizes a molten liquid as a binder(s) or granulation
matrix in which the active pharmaceutical ingredient (API) is mixed and then cooled
down followed by milling into powder. This is usually accomplished in a temperature
controlled jacketed high shear granulating tank or using a heated nozzle that sprays
the molten binders(s) onto the fluidizing bed of the API and other inactive ingredients.;
Origin ID : C113009;
UMLS CUI : C3830095;
Semantic type(s)
- concept_is_in_subset
