Hepsulfam - CISMeF

Preferred Label : Hepsulfam;

NCIt synonyms : 1,7-Heptanediyl Ester Sulfamic Acid;

NCIt related terms : Sulfamic acid, 1,7-heptanediyl ester;

NCIt definition : A bisulfamic ester which is similar in structure to busulfan and belongs to the family of drugs known as alkylsulfonate alkylating agents. Hepsulfam forms covalent linkages with nucleophilic centers in DNA, resulting in depurination, base miscoding, strand scission, DNA-DNA and DNA-protein cross-linking, and cytotoxicity. (NCI04);

UNII : 971DU2GQ51;

CAS number : 96892-57-8;

NSC code : 329680;

Codes from synonyms : NSC0329680;

Details

Origin ID

C1123;

UMLS CUI

C0062540;

Currated CISMeF NLP mapping
- hepsulfam [MeSH concept]
- hepsulfam [MeSH Supplementary Concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- hepsulfam [MeSH concept]
- hepsulfam [MeSH Supplementary Concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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