NCIt definition : A genus of non-enveloped, spherical viruses with T pseudo3 icosahedral capsid, in
the family Picornaviridae. The genome is composed of a linear, single-strand of positive
sense, naked RNA. Aphthoviruses are found in cloven-hooved animals and cause foot-and-mouth
disease in humans.;
Alternative definition : CDISC: Any viral organism that can be assigned to the genus Aphthovirus.;