Tn Antigen - CISMeF

Preferred Label : Tn Antigen;

NCIt synonyms : CD175; Tn;

NCIt definition : A protein antigen that is comprised of the monosaccharide N-acetylgalactosamine (GalNAc) bound to serine or threonine by O-linked glycosylation. Aberrant expression of Tn antigen by all blood cell lineages is associated with a rare hematological disorder called Tn-syndrome. Increased expression of this monosaccharide modification is also associated with some cancers and this antigen is being investigated for use as either a biomarker or therapeutic target for these associated malignancies.;

Details

Origin ID

C112044;

UMLS CUI

C0076765;

Automatic exact mappings (from CISMeF team)
- Tenascin C [OMIM gene]
- tenascin C [ORDO Gene]
- tn antigen [MeSH Supplementary Concept]
- tn antigen [MeSH concept]
Semantic type(s)
- Immunologic Factor [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- tn antigen [MeSH Supplementary Concept]
- tn antigen [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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