Preferred Label : Yangzheng Xiaoji Extract;
NCIt synonyms : YZXJ Extract;
NCIt definition : A traditional Chinese medicine (TCM)-based formulation containing the Yangzheng Xiaoji
(YZXJ) extract, consisting of various components, with potential antineoplastic and
anti-angiogenic activities. Some of the main components in Yangzheng Xiaoji are Radix
Astragali, Fructus Ligustri Lucidi, Radix Ginseng, Ganoderma, Rhizoma Curcumac, Fried
Rhizoma Atractylodis, Macrocephalae and Herba Hedyotidis. Although the exact mechanism(s)
through which Yangzheng Xiaoji exerts its effects have yet to be fully elucidated,
this agent, upon administration, inhibits the activation of various signaling protein
kinases, such as focal adhesion kinase (FAK) and paxillin. This prevents signal transduction
pathways that are upregulated in cancer, prevents the adhesion and migration of tumor
cells and inhibits tumor cell growth.;
Molecule name : DME25;
Origin ID : C111897;
UMLS CUI : C3827131;
Semantic type(s)
- concept_is_in_subset
