Preferred Label : Sorghum bicolor Supplement;
NCIt synonyms : Sorghum bicolor Extract;
NCIt definition : An herbal-based nutritional supplement containing the leaf sheaths of the plant Sorghum
bicolor, with potential antioxidant, anti-inflammatory, chemopreventive and immunomodulating
activities. Sorghum bicolor supplement contains various phytochemicals, including
phenolic acids and polyphenols such as proanthocyanidins. Sorghum bicolor supplement
is particularly rich in 3-deoxyanthocyanins, such as luteolinidin and apigeninidin,
and appears to induce apoptosis and inhibit cell proliferation in cancer cells through
the stimulation of various apoptosis promoter genes and the downregulation of certain
apoptosis inhibitor genes. In addition, due to the strong antioxidant nature of the
phytochemicals, these compounds are able to scavenge free radicals and prevent tissue
damage. Also, intake of this supplement modulates the immune system by both increasing
the activity of natural killer (NK) cells and initiating the activation of macrophages.;
Drug name : Jobelyn;
NCI Metathesaurus CUI : CL454073;
Origin ID : C111681;
UMLS CUI : C3827970;
Semantic type(s)
- concept_is_in_subset
