NCIt related terms : Kymarabine; 1,3, 5-Triazin-2(1H)-one, 4-amino-1-.beta.-D- arabinofuranosyl- (9CI); 1-.beta.-D-Arabinofuranosyl-5-azacytosine; Ara AC;
NCIt definition : An orally-active pyrimidine analogue of an aza-substituted cytidine in which the ribose
moiety is replaced by an arabinose sugar. Similar in action to cytarabine, fazarabine
is phosphorylated by deoxycytidine kinase to a triphosphate form which competes with
thymidine for incorporation into DNA; its incorporation into DNA inhibits DNA synthesis,
resulting in tumor cell death and tumor necrosis. The presence of deoxycytidine kinase
in a tumor is a determinant of tumor sensitivity to this drug. (NCI04);
Alternative definition : NCI-GLOSS: An anticancer drug that is a type of antimetabolite.;
UNII : 5V71D8JOKK;
InChIKey : NMUSYJAQQFHJEW-ARQDHWQXSA-N;
CAS number : 65886-71-7; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 65886-71-7
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