Toxic Shock Syndrome Toxin-1

Preferred Label : Toxic Shock Syndrome Toxin-1;

NCIt synonyms : TSST-1;

NCIt definition : Staphylococcal toxic shock syndrome toxin 1. A superantigen with the potential to suppress plasma cell differentiation and antibody responsiveness. Potent pyrogen, induces T lymphocyte proliferation, requiring interleukin 1 release from macrophages, suppresses immunoglobulin production, enhances endotoxin shock, and enhances hypersensitivity skin reactions. Causes staphylococcal toxic shock syndrome (TSS).;

Details

Origin ID

C1086;

UMLS CUI

C1617068;

Automatic exact mappings (from CISMeF team)
- Staphylococcus aureus toxic shock syndrome toxin 1 (substance) [SNOMED CT concept]
- TST protein, staphylococcus aureus [MeSH concept]
- Toxic shock syndrome toxin 1 (qualifier value) [SNOMED CT concept]
- enterotoxin F, Staphylococcal [MeSH Supplementary Concept]
Currated CISMeF NLP mapping
- toxic shock syndrome toxin 1 (101-158) [MeSH concept]
- toxic shock syndrome toxin 1 (101-158) [MeSH Supplementary Concept]
- toxic shock syndrome toxin 1 (125-158) [MeSH concept]
- toxic shock syndrome toxin 1 (125-158) [MeSH Supplementary Concept]
- toxic shock syndrome toxin-1 (58-78) [MeSH concept]
- toxic shock syndrome toxin-1 (58-78) [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
UMLS correspondences (same concept)
- Staphylococcus aureus toxic shock syndrome toxin 1 [LOINC component]
- Staphylococcus aureus toxic shock syndrome toxin 1 (substance) [SNOMED CT concept]
- TST protein, staphylococcus aureus [MeSH concept]
- Toxic shock syndrome toxin 1 (qualifier value) [SNOMED CT concept]

Keyword's position in hierarchy(ies) :

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