Elsamitrucin - CISMeF

Preferred Label : Elsamitrucin;

NCIt synonyms : Elsamicin A; Elsamitrucina; Benzo(h)(1)benzopyrano(5,4,3-cde)(1)ebnzopyran-5,12-dione,10((2-O-(2-amino-2,6-dideoxy-3-O-methyl-alpha-D-galactopyranosyl)-6-deoxy-3-C-methyl-beta-D-galactopyranosyl)oxy)-6-hydroxy-1-methyl; Elsamitrucine; Elsamitrucinum; 10-O-Elsaminosylelsarosylchartarin;

NCIt definition : An heterocyclic antineoplastic antibiotic isolated from the bacterium Actinomycete strain J907-21. Elsamitrucin intercalates into DNA at guanine-cytosine (G-C)-rich sequences and inhibits topoisomerase I and II, resulting in single-strand breaks and inhibition of DNA replication. (NCI04);

UNII : ZTV0FOB6NU;

InChIKey : MGQRRMONVLMKJL-KWJIQSIXSA-N;

CAS number : 97068-30-9; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 97068-30-9 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Molecule name : BBM 2478A; BRN 5214813; BMY-28090;

Chemical formula : C33H35NO13;

Details

Origin ID

C1080;

UMLS CUI

C0059041;

Currated CISMeF NLP mapping
- elsamicin A [MeSH concept]
- elsamicin A [MeSH Supplementary Concept]
Semantic type(s)
- Antibiotic [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- elsamicin A [MeSH Supplementary Concept]
- elsamicin A [MeSH concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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