NCIt definition : An enediyne antineoplastic antibiotic hybrid containing an anthraquinone moiety isolated
from the bacterium Micromonospora chersina. The anthraquinone moiety intercalates
into DNA and the benzene diradical intermediate of the enediyne core binds to the
minor groove of DNA, resulting in double-strand breaks in DNA, inhibition of DNA replication
and apoptosis. (NCI04);