Preferred Label : Liposomal Rhenium Re 186;
NCIt synonyms : Rhenium-186 Liposome; 186RNL; Liposomal Rhenium-186; (186)Re-Liposomes;
NCIt definition : A therapeutic preparation consisting of the beta-emitting radioisotope rhenium Re
186 encapsulated in a nanoliposome, with potential antineoplastic activity. Upon intratumoral
infusion of liposomal rhenium Re 186, the radioisotope releases radiation, which directly
kills the tumor cells. The nanoliposomes facilitate the retention of the radioisotope
by the tumor cells and localize the radiocytotoxicity to the tumor while sparing surrounding
normal, healthy cells. Re-186 has a short half-life and a short path length, which
contributes further to limiting the radiotoxicity to the tumor cells.;
NCI Metathesaurus CUI : CL451869;
Origin ID : C107679;
UMLS CUI : C3827043;
Semantic type(s)
- concept_is_in_subset
