B-Cell Receptor Complex

Preferred Label : B-Cell Receptor Complex;

NCIt synonyms : B Cell Receptor Complex; B-Cell Receptor; BCR; B-Cell Antigen Receptor Complex; B Cell Receptor;

NCIt definition : A membrane bound protein complex comprised of an immunoglobulin molecule associated with a heterodimer, called CD79, containing one CD79A protein and one CD79B protein. The immunoglobulin determines the ligand specificity of the complex and the CD79 heterodimer promotes signal transduction. This receptor is involved in antigen processing and presentation.;

Details

Origin ID

C107558;

UMLS CUI

C3816168;

Automatic exact mappings (from CISMeF team)
- B cell receptor [COVID-19 Thesaurus concept]
- B cell receptor complex [GO term]
- B cell receptor complex [OBI concept]
- BCR [LOINC component]
- BCR activator of RhoGEF and GTPase [ORDO Gene]
- Bcr activator of rhogef and gtpase [OMIM gene]
- receptors, antigen, B-Cell [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_product_has_biochemical_function
- Cell Surface Receptor [NCIt concept]
- Immunoprotein [NCIt concept]
gene_product_plays_role_in_biological_process
- Antigen Presentation [NCIt concept]
- Antigen Processing [NCIt concept]
- Signal Transduction Induction [NCIt concept]
has_gene_product_element
- B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain [NCIt concept]
- B-Cell Antigen Receptor Complex-Associated Protein Beta Chain [NCIt concept]
- CD79 [NCIt concept]

Keyword's position in hierarchy(ies) :

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