Preferred Label : Nogapendekin Alfa;
NCIt definition : A mutated form of the cytokine interleukin (IL)-15 (IL-15N72D), with potential immunomodulating
and antineoplastic activities. Upon administration, nogapendekin alfa binds to the
IL-15 receptor on natural killer (NK) and CD8 T lymphocytes, which activates and
increases the levels of NK cells and memory T-cells. This may increase tumor cell
killing and decrease tumor cell proliferation. IL-15 regulates CD8 T and NK cell
development, activation and proliferation.;
UNII : EW92EB4VEN;
CAS number : 1622189-43-8;
Origin ID : C107503;
UMLS CUI : C5418154;
Semantic type(s)
- UMLS correspondences (same concept)
- ALT-803 [MeSH Supplementary Concept]
- concept_is_in_subset
