Dimethylmyleran

Preferred Label : Dimethylmyleran;

NCIt synonyms : Dimethylbusulfan; Dimethyl-Myleran; 2,5-Dimethanesulfonoxyhexane; DMB; DMM;

NCIt definition : An aliphatic analogue of busulfan with potential antineoplastic activity. As an alkylating agent, dimethylbusulfan induces neutropenia and has been shown to exhibit antitumor effects in some animal models. Alkylating agents exert cytotoxic and chemotherapeutic effects by transferring alkyl groups to DNA, thereby damaging DNA and interfering with DNA synthesis and cell division. (NCI04);

CAS number : 55-93-6;

NSC code : 180542; 23890; 180543; 180541;

Codes from synonyms : NSC0023890;

Details

Origin ID

C1073;

UMLS CUI

C0058272;

Automatic exact mappings (from CISMeF team)
- Becker muscular dystrophy [ORDO Disease]
Currated CISMeF NLP mapping
- dimethylmyleran [MeSH concept]
- dimethylmyleran [MeSH Supplementary Concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- dimethylmyleran [MeSH concept]
- dimethylmyleran [MeSH Supplementary Concept]
concept_is_in_subset
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
is_component_of_chemotherapy_regimen
- Dimethylbusulfan/Etoposide [NCIt concept]

Keyword's position in hierarchy(ies) :

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