Preferred Label : Allogeneic HLA-A2/4-1BB ligand-expressing Melanoma Vaccine;
NCIt definition : An allogeneic melanoma cell vaccine derived from a cell line with high expression
of melanoma associated antigens and genetically modified to express both HLA-A2 and
4-1BB ligand, with potential immunostimulating and antineoplastic activities. Upon
administration, the 4-1BB ligand of the allogeneic HLA-A2/4-1BB ligand-expressing
melanoma vaccine binds to 4-1BB on activated T-lymphocytes, which induces a strong
immune response against HLA-A2 positive melanoma cells.;
NCI Metathesaurus CUI : CL449429;
Origin ID : C107169;
UMLS CUI : C3831561;
Semantic type(s)
- Cell [UMLS semantic type]
- concept_is_in_subset
