Preferred Label : Heparan Sulfate Glycosaminoglycan Mimetic Nanopolymer Mouthwash;
NCIt synonyms : MUCIPLIQ Mouthwash;
NCIt definition : A nanopolymer-based mouthwash formulation containing a mimetic of the glycosaminoglycan
(GAG) heparan sulfate, with potential anti-mucositic and protective activities. Upon
rinsing with the mouthwash, GAGs bind to heparan sulfate binding sites on macromolecules
within the extracellular matrix (EMC), which prevents the destruction of the ECM and
protects both growth factors and cytokines from being degraded. By replacing the GAGs
damaged by chemotherapy and/or radiation, this mouthwash may protect healthy tissue
against the cytotoxic effects of chemotherapy and radiation and may prevent against
radio-chemotherapy-induced mucositis.;
NCI Metathesaurus CUI : CL449422;
Origin ID : C107161;
UMLS CUI : C3829710;
Semantic type(s)
- concept_is_in_subset
