NDN wt Allele - CISMeF

Preferred Label : NDN wt Allele;

NCIt synonyms : PWCR; Prader-Willi Syndrome Chromosome Region Gene; HsT16328; Necdin Homolog Gene; Necdin, MAGE Family Member wt Allele; Necdin Homolog (Mouse) Gene; Necdin (Mouse) Homolog Gene; Necdin, Melanoma Antigen (MAGE) Family Member Gene;

NCIt definition : Human NDN wild-type allele is located in the vicinity of 15q11.2 and is approximately 2 kb in length. This allele, which encodes necdin protein, is involved in suppression of cell growth in postmitotic neurons. Mutations in this gene are associated with Prader-Willi syndrome.;

GenBank Accession Number : NM_002487;

Details

Origin ID

C107135;

UMLS CUI

C3813582;

Automatic exact mappings (from CISMeF team)
- Prader-willi syndrome [OMIM Phenotype]
- necdin, MAGE family member [ORDO Gene]
OMIM relation
- Necdin [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 15q11.2 [NCIt concept]
gene_plays_role_in_process
- Cell Cycle Process [NCIt concept]
- Cell Cycle Regulation Process [NCIt concept]
- Cell Growth Regulation [NCIt concept]
- DNA Binding [NCIt concept]
- Transcriptional Regulation [NCIt concept]
- Transcriptional Repression [NCIt concept]

Keyword's position in hierarchy(ies) :

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