Mothers Against Decapentaplegic Homolog 1

Preferred Label : Mothers Against Decapentaplegic Homolog 1;

NCIt synonyms : Transforming Growth Factor-Beta Signaling Protein 1; TGF-Beta Signaling Protein 1; MAD, Mothers Against Decapentaplegic Homolog 1; MAD Homolog 1; MAD, Mothers Against Decapentaplegic Homolog 1 (Drosophila); Transforming Growth Factor-Beta-Signaling Protein 1; Mothers Against DPP Homolog 1; Mad-Related Protein 1; SMAD, Mothers Against DPP Homolog 1 (Drosophila);

NCIt definition : Mothers against decapentaplegic homolog 1 (465 aa, 52 kDa) is encoded by the human SMAD1 gene. This protein plays a role in regulating the action of bone morphogenic proteins in cell growth, apoptosis, morphogenesis, development and immune responses.;

Details

Origin ID

C106613;

UMLS CUI

C0528559;

Automatic exact mappings (from CISMeF team)
- Smad family member 1 [OMIM gene]
OMIM relation
- Smad family member 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- SMAD1 protein, human [MeSH Supplementary Concept]
- SMAD1 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Adaptor Signaling Protein Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
- SMAD1 Gene [NCIt concept]
- Signaling Pathway Gene [NCIt concept]
- Transcription Factor Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- DNA Binding Protein [NCIt concept]
- Sequence-Specific DNA Binding Protein [NCIt concept]
gene_product_is_element_in_pathway
- ALK Pathway [NCIt concept]
- CTCF Pathway [NCIt concept]
- TGF-beta Signaling Pathway KEGG [NCIt concept]
gene_product_plays_role_in_biological_process
- DNA Binding [NCIt concept]
- Protein-Protein Interaction [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]
- Subcellular Protein Targeting [NCIt concept]
- Transcriptional Activation [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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