Preferred Label : Detorubicin;
NCIt synonyms : Diethoxy-,2-(4-((3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-1,2,3,4,6,11-hexahydro-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-2-naphthacenyl)-2-oxoethyl
ester,(2S-cis) Acetic Acid; 14-Diethoxyacetoxydaunorubicin;
NCIt definition : A semi-synthetic derivative of the anthracycline antineoplastic antibiotic daunorubicin.
Detorubicin intercalates into DNA and interacts with topoisomerase II, thereby inhibiting
DNA replication and repair and RNA and protein synthesis. This agent also produces
toxic free-radical intermediates and interacts with cell membrane lipids causing lipid
peroxidation. Detorubicin is less toxic than daunorubicin.;
UNII : 822EC3XEJZ;
InChIKey : XZSRRNFBEIOBDA-CFNBKWCHSA-N;
CAS number : 66211-92-5; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 66211-92-5
alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo
G-SRS /a ;
Chemical formula : C33H39NO14;
NSC code : 292652;
Origin ID : C1066;
UMLS CUI : C0057578;
Currated CISMeF NLP mapping
- Semantic type(s)
- UMLS correspondences (same concept)
- concept_is_in_subset
