Preferred Label : Topical Menthol Cream;
NCIt definition : A topical cream containing menthol that both causes a localized cooling sensation
and has analgesic activities. Upon topical application, menthol acts on the cold-sensitive
transient receptor potential cation channel subfamily M member 8 (TMPR8), which provides
a cooling sensation. This treatment also provides an analgesic effect through the
activation of the inhibitory Group II/III metabotropic glutamate receptors (mGluRs).
This may decrease neuropathic pain from chemotherapy. In addition, the topical application
of menthol causes vasodilation.;
Origin ID : C106431;
UMLS CUI : C1251984;
Semantic type(s)
- concept_is_in_subset
