HCRT wt Allele

Preferred Label : HCRT wt Allele;

NCIt synonyms : NRCLP1; Hypocretin (Orexin) Neuropeptide Precursor wt Allele; OX; PPOX;

NCIt definition : Human HCRT wild-type allele is located in the vicinity of 17q21 and is approximately 1 kb in length. This allele, which encodes orexin protein, plays a role in both G-protein coupled receptor signaling and feeding behavior. Mutation of the gene is associated with narcolepsy 1.;

GenBank Accession Number : AF041240;

Détails

Origin ID

C106420;

UMLS CUI

C3811761;

Automatic exact mappings (from CISMeF team)
- Beef [LOINC component]
- Hypocretin [OMIM gene]
- Narcolepsy 1 [OMIM Phenotype]
- Ox (organism) [SNOMED CT concept]
- Protoporphyrinogen oxidase [OMIM gene]
- cattle [MeSH Descriptor]
- hypocretin neuropeptide precursor [ORDO Gene]
- narcolepsy 1 [MeSH Supplementary Concept]
- protoporphyrinogen oxidase [ORDO Gene]
OMIM relation
- Hypocretin [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 17q21 [NCIt concept]
gene_is_element_in_pathway
- Neuroactive Ligand-Receptor Signaling Pathway [NCIt concept]
gene_plays_role_in_process
- Appetite [NCIt concept]
- G Protein-Coupled Receptor Signaling [NCIt concept]
- Neuronal Transmission [NCIt concept]

Position du mot-clé dans l'(les) arborescence(s) :

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