Defibrotide Sodium

Preferred Label : Defibrotide Sodium;

NCIt synonyms : Prociclide; Fraction P; Defibrinotide; Defibrotide;

NCIt definition : A polydeoxyribonucleotide with antithrombotic, thrombolytic, and fibrinolytic properties. Defibrotide induces the release of prostaglandin 12 and reduces the expression of adhesion molecules on endothelial cells, thereby interfering with platelet and leukocyte adhesion to the endothelium. (NCI04);

Alternative definition : NCI-GLOSS: A drug under study for the prevention of veno-occlusive disease, a rare complication of high-dose chemotherapy and stem cell transplantation in which small veins in the liver become blocked.;

UNII : L7CHH2B2J0;

CAS number : 83712-60-1;

Drug name : Noravid; Defitelio;

Codes from synonyms : CDR0000046709;

Details

Origin ID

C1064;

UMLS CUI

C4224791;

Currated CISMeF NLP mapping
- Defibrotide sodium [SMS substance]
- Defibrotide sodium (substance) [SNOMED CT concept]
- defibrotide sodium [MeSH concept]
See also inter- (CISMeF)
- Product containing defibrotide (medicinal product) [SNOMED CT concept]
- defibrotide [ATC Code]
Semantic type(s)
- Nucleic Acid, Nucleoside, or Nucleotide [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Defibrotide sodium (substance) [SNOMED CT concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
has_free_acid_or_base_form
- Defibrotide [NCIt concept]
is_salt_form_of
- Defibrotide [NCIt concept]

Keyword's position in hierarchy(ies) :

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