Cip1-Interacting Zinc Finger Protein

Preferred Label : Cip1-Interacting Zinc Finger Protein;

NCIt synonyms : CDKN1A-Interacting Zinc Finger Protein 1; Nuclear Protein NP94; Zinc Finger Protein 356; CIZ1;

NCIt definition : Cip1-interacting zinc finger protein (898 aa, 100 kDa) is encoded by the human CIZ1 gene. This protein plays a role in the modulation of both cyclin-dependent kinase inhibitor 1 protein localization and DNA replication.;

NCIt note : The expression of a newly described variant form of Cip1-interacting zinc finger protein, which has an in-frame deletion of eight amino acids (758-765; VEEELCKQ), may be a biomarker for early-stage lung cancer. (PNAS. 2012; 109:E3128-E3135 .);

Details

Origin ID

C106351;

UMLS CUI

C3813547;

Automatic exact mappings (from CISMeF team)
- CDKN1A interacting zinc finger protein 1 [ORDO Gene]
- Cdkn1a-interacting zinc finger protein 1 [OMIM gene]
OMIM relation
- Cdkn1a-interacting zinc finger protein 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
gene_encodes_gene_product
- CIZ1 Gene [NCIt concept]
- Cell Cycle Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- Regulatory Protein [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Cycle Regulation Process [NCIt concept]
- Replication-Associated Process [NCIt concept]
- S Phase Process [NCIt concept]
- Subcellular Protein Targeting [NCIt concept]

Keyword's position in hierarchy(ies) :

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