Preferred Label : WT1 Peptide Vaccine OCV-501;
NCIt definition : A peptide cancer vaccine comprised of a peptide derived from Wilms tumor gene 1 (WT1)
protein, with potential immunomodulating and antineoplastic activities. Upon subcutaneous
administration, WT1 peptide vaccine OCV-501 may stimulate a CD4-positive helper T-lymphocyte-mediated
immune response against WT1 expressing cells. WT1 protein, a zinc finger DNA-binding
protein, is overexpressed in leukemic cells and in some solid tumors.;
Molecule name : OCV-501;
NCI Metathesaurus CUI : CL433890;
Origin ID : C106257;
UMLS CUI : C3827094;
Semantic type(s)
- chemical_or_drug_has_mechanism_of_action
- concept_is_in_subset
