CBFA2T3/GLIS2 Fusion Gene

Preferred Label : CBFA2T3/GLIS2 Fusion Gene;

NCIt synonyms : CBFA2T3-GLIS2 Fusion Gene; CBFA2T3::GLIS2 Fusion Gene;

NCIt definition : A fusion gene that results from a chromosomal translocation inv(16)(p13q24) which fuses either the first 10 or 11 exons of the CBFA2T3 gene with either exon 1 or exon 3 of the GLIS2 gene. This fusion is associated with acute megakaryoblastic leukemia.;

Details

Origin ID

C105819;

UMLS CUI

C3831174;

Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- CBFA2T3/GLIS2 Fusion Protein [NCIt concept]
gene_involved_in_molecular_abnormality
- inv(16)(p13.3;q24.3) [NCIt concept]
gene_involved_in_pathogenesis_of_disease
- Acute Megakaryoblastic Leukemia with CBFA2T3-GLIS2 [NCIt concept]
gene_mapped_to_disease
- Acute Megakaryoblastic Leukemia with CBFA2T3-GLIS2 [NCIt concept]
gene_plays_role_in_process
- Transcriptional Regulation [NCIt concept]
related_to_genetic_biomarker
- CBFA2T3 Gene [NCIt concept]
- GLIS2 Gene [NCIt concept]

Keyword's position in hierarchy(ies) :

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