Keratin, Type II Cytoskeletal 5

Preferred Label : Keratin, Type II Cytoskeletal 5;

NCIt synonyms : CK-5; Keratin-5; Type-II Keratin Kb5; Cytokeratin-5; KRT5; 58 kDa Cytokeratin; K5;

NCIt definition : Keratin, type II cytoskeletal 5 (590 aa, 62 kDa) is encoded by the human KRT5 gene. This protein is involved in the structure of the epidermis.;

NCIt note : Keratin, type II cytoskeletal 5 in the epidermis is part of a heterotetramer consisting of two keratin, type I cytoskeletal 14 chains and two keratin, type II cytoskeletal 5 chains. (UniProt);

Details

Origin ID

C105681;

UMLS CUI

C1620063;

Automatic exact mappings (from CISMeF team)
- Keratin 5, type II [OMIM gene]
- Keratin-5 [MeSH Descriptor]
- Keratin-5 [MeSH concept]
- keratin 5 [ORDO Gene]
OMIM relation
- Keratin 5, type II [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- KRT5 protein, human [MeSH concept]
- KRT5 protein, human [MeSH Supplementary Concept]
- Keratin-5 [MeSH Descriptor]
- Keratin-5 [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Cytoskeletal Gene [NCIt concept]
- Intermediate Filament Gene [NCIt concept]
- KRT5 Gene [NCIt concept]
- Structural Protein Gene [NCIt concept]
gene_product_expressed_in_tissue
- Epidermis [NCIt concept]
gene_product_has_associated_anatomy
- Cytoskeleton [NCIt concept]
- Hemidesmosome [NCIt concept]
- Intermediate Filament [NCIt concept]
- Keratin Filament [NCIt concept]
gene_product_has_biochemical_function
- Scaffolding Protein [NCIt concept]
gene_product_has_chemical_classification
- Cytokeratin [NCIt concept]
gene_product_is_element_in_pathway
- Glucocorticoid Receptor Regulatory Network [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Movement Process [NCIt concept]
- Cytoskeletal Process [NCIt concept]
- Keratinization [NCIt concept]
- Organogenesis [NCIt concept]
- Protein-Protein Interaction [NCIt concept]
- Regulation of Cell Shape [NCIt concept]

Keyword's position in hierarchy(ies) :

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