NCIt definition : An epidermal growth factor receptor (EGFR) inhibitor, with potential antineoplastic
activity. Upon intravenous infusion, depatuxizumab mafodotin inhibits the activity
of EGFR, thereby preventing EGFR-mediated signaling. This may inhibit tumor growth
in EGFR-overexpressing tumor cells. EGFR, a receptor tyrosine kinase overexpressed
in certain tumor cell types, plays a key role in tumor cell proliferation and tumor
vascularization.;
UNII : F3R7A4P04N;
CAS number : 1585973-65-4; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 1585973-65-4
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