Lamina-Associated Polypeptide 2, Isoforms Beta/Gamma

Preferred Label : Lamina-Associated Polypeptide 2, Isoforms Beta/Gamma;

NCIt synonyms : LEM Domain Containing 4; Thymopoietin-Related Peptide Isoforms Beta/Gamma; Thymopoietin; TPRP Isoforms Beta/Gamma; TP Beta/Gamma; TMPO; Lamina-Associated Polypeptide 2; Thymopoietin, Isoforms Beta/Gamma;

NCIt definition : Lamina-associated polypeptide 2, isoforms beta/gamma (694 aa, 75 kDa) is encoded by the human TMPO gene. This protein is involved in the mediation of nuclear structure.;

NCIt note : Lamina-associated polypeptide 2, isoforms beta/gamma is a transmembrane protein in the inner nuclear membrane. (UniProt); Lamina-associated polypeptide 2, isoforms beta/gamma is cleaved to form 2 polypeptides: thymopoietin (TP, Splenin) and thymopentin (TP5). Both polypeptides play a role in T-cell function. (UniProt);

Details

Origin ID

C105103;

UMLS CUI

C3538882;

Automatic exact mappings (from CISMeF team)
- 3,3,5,5-tetramethyl-1-pyrroline N-oxide [MeSH Supplementary Concept]
- Thymopoietin [OMIM gene]
- lamina-associated polypeptide 2 [MeSH concept]
- lamina-associated polypeptide 2 [MeSH Supplementary Concept]
- thymopoietin [ORDO Gene]
- thymopoietin [HGNC gene]
- thymopoietins [MeSH Descriptor]
- thymopoietins [MeSH concept]
OMIM relation
- Thymopoietin [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Peptide Hormone Gene [NCIt concept]
- TMPO Gene [NCIt concept]
gene_product_expressed_in_tissue
- Thymus Gland [NCIt concept]
gene_product_has_associated_anatomy
- Nuclear Inner Membrane [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_plays_role_in_biological_process
- Intercellular Communication Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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