Negative Elongation Factor C/D

Preferred Label : Negative Elongation Factor C/D;

NCIt synonyms : NELF-C/D; NELFCD; Trihydrophobin 1; TH1-Like Protein; Negative Elongation Factor Proteins C and D;

NCIt definition : Negative elongation factor C/D (590 aa, 66 kDa) is encoded by the human NELFCD gene. This protein is involved in transcriptional pausing.;

NCIt note : Usage of alternative translation initiation sites results in the formation of two isoforms, NELF-C and NELF-D. NELF-D lacks the first 9 amino acids found in NELF-C. (EntrezGene and UniProt);

Details

Origin ID

C105099;

UMLS CUI

C3537293;

OMIM relation
- Negative elongation factor complex, member C/d [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- NELFCD Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_has_biochemical_function
- Transcription Repressor/Corepressor [NCIt concept]
gene_product_plays_role_in_biological_process
- Transcription Elongation [NCIt concept]
- Transcriptional Regulation [NCIt concept]
- Transcriptional Repression [NCIt concept]

Keyword's position in hierarchy(ies) :

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