CR2 wt Allele - CISMeF

Preferred Label : CR2 wt Allele;

NCIt synonyms : SLEB9; Complement Component (3d/Epstein Barr Virus) Receptor 2 wt Allele; CD21; CVID7; CR; RP11-78B10.1; C3DR;

NCIt definition : Human CR2 wild-type allele is located in the vicinity of 1q32 and is approximately 36 kb in length. This allele, which encodes complement receptor type 2 protein, is involved in the activation of both B-cells and complement-mediated immunity. Mutation of the gene is associated with systemic lupus erythematosus type 9.;

GenBank Accession Number : M26004;

Details

Origin ID

C104978;

UMLS CUI

C3539604;

Automatic exact mappings (from CISMeF team)
- CD21 [LOINC component]
- CD21 Ag [LOINC component]
- CD21 cells [LOINC component]
- CD55 molecule (Cromer blood group) [ORDO Gene]
- Complement component receptor 2 [OMIM gene]
- Delayed-Action preparations [MeSH Descriptor]
- Immunodeficiency, common variable, 7 [OMIM Phenotype]
- Lymphocyte antigen CD21 (substance) [SNOMED CT concept]
- Systemic lupus erythematosus, susceptibility to, 9 [OMIM Phenotype]
- birth rate [MeSH Descriptor]
- capsule of red nucleus [UBERON concept]
- complement C3d receptor 2 [ORDO Gene]
- conditioning, classical [MeSH Descriptor]
- crisamicin A [MeSH Supplementary Concept]
- receptors, complement 3d [MeSH Descriptor]
- teratocarcinoma-derived growth factor 1 [ORDO Gene]
OMIM relation
- Complement component receptor 2 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 1q32 [NCIt concept]
gene_is_element_in_pathway
- B Cell Receptor Signaling Pathway [NCIt concept]
- Complement and Coagulation Cascade [NCIt concept]
- Hematopoietic Cell Lineage Pathway [NCIt concept]
gene_plays_role_in_process
- Complement Activation [NCIt concept]
- Immunity [NCIt concept]
- Ligand Binding [NCIt concept]
- Receptor Signaling [NCIt concept]

Keyword's position in hierarchy(ies) :

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