Tribbles Homolog 2

Preferred Label : Tribbles Homolog 2;

NCIt synonyms : TRIB2; TRB-2;

NCIt definition : Tribbles homolog 2 (343 aa, 39 kDa) is encoded by the human TRIB2 gene. This protein is involved in the modulation of MAP kinase activation.;

NCIt note : Tribbles homolog 2 is homologous to protein serine-threonine kinases, but is lacking the active site lysine and has no catalytic activity. (UniProt);

Details

Origin ID

C104577;

UMLS CUI

C3541919;

OMIM relation
- Tribbles pseudokinase 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Signaling Pathway Gene [NCIt concept]
- TRIB2 Gene [NCIt concept]
gene_product_expressed_in_tissue
- Leukocyte [NCIt concept]
gene_product_has_associated_anatomy
- Cytoskeleton [NCIt concept]
gene_product_plays_role_in_biological_process
- Enzyme Activity Alteration [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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