Preferred Label : Zirconium Zr 89 DFO-MSTP2109A;
NCIt synonyms : 89Zr-DFO-MSTP2109A;
NCIt definition : A radioimmunoconjugate composed of the radioisotope zirconium Zr 89 conjugated to
an antibody that targets six transmembrane epithelial antigen of the prostate 1 (STEAP1)
that can potentially be used as a prostate cancer tracer during positron emission
tomography (PET). Upon administration of zirconium Zr 89 DFO-MSTP2109A, the antibody
moiety DFO-MSTP2109A binds to STEAP1 on prostate cancer cells. In turn, Zr 89 allows
for the visualization of those cells using PET. STEAP1, a six-transmembrane domain
protein, is overexpressed on the surface of prostate cancer cells.;
NCI Metathesaurus CUI : CL445685;
Origin ID : C104420;
UMLS CUI : C3641796;
Semantic type(s)
- concept_is_in_subset
- has_target
