Preferred Label : Fluorine F 18-labeled S-(3-Fluoropropyl)homocysteine Hydrochloride;
NCIt synonyms : [(18)F]FPHCys; 18F-FPM;
NCIt related terms : (18F)-D-FPHCYS;
NCIt definition : The hydrochloride salt form of a radioconjugate composed of a synthetic derivative
of the amino acid methionine radiolabeled with fluoride F 18, with potential use as
a tumor imaging agent during positron emission tomography (PET). Upon administration,
fluorine F 18-labeled S-(3-fluoropropyl) homocysteine is preferentially taken up by
tumor cells through an amino acid transporter, which is overexpressed by cancer cells.
As tumor cells have a higher rate of proliferation than normal cells, these cancer
cells have increased rates of protein synthesis and thus an increased demand for amino
acids. This allows for visualization of tumors cells upon PET.;
UNII : 4G7MR2WS1V;
CAS number : 1245941-98-3;
NCI Metathesaurus CUI : CL445614;
Origin ID : C104269;
UMLS CUI : C3641738;
Semantic type(s)
- concept_is_in_subset
